Rodrigues, Fiona C Hari, Gangadhar Pai, K S R Suresh, Akhil Nayak, Usha Y Anilkumar, N V Thakur, Goutam
Published in
3 Biotech
The human Abl kinases comprise a family of proteins that are known to be key stimulus drivers in the signaling pathways modulating cell growth, cell survival, cell adhesion, and apoptosis. Recent collative studies have indicated the role of activation of Abl and Abl-related genes in solid tumors; further terming the Abl kinases as molecular switche...
Singh, Sudiksha Ramakrishna, Wusirika
Published in
3 Biotech
Agriculture's beginnings resulted in the domestication of numerous plant species as well as the use of natural resources. Food grain production took about 10,000 years to reach a billion tonnes in 1960, however, it took only 40 years to achieve 2 billion tonnes in year 2000. The creation of genetically modified crops, together with the use of enhan...
Bhagavatham, Sai Krishna Srimadh Kannan, Vishnu Darshan, V M Datta Sivaramakrishnan, Venketesh
Published in
3 Biotech
P2 receptors are nucleotide-activated receptors involved in inflammation, cell proliferation osteoblastogenesis, osteoclastogenesis and their function. They can be potential role players in the pathophysiology of rheumatoid arthritis (RA). Our analysis of gene expression datasets of synovial tissue biopsy from the GEO database shows changes in the ...
Samarpita, Snigdha Doss, Hari Madhuri Ganesan, Ramamoorthi Rasool, Mahaboobkhan
Published in
3 Biotech
Majoon Chobchini, a polyherbal Unani compound, has been used holistically in India to treat rheumatoid arthritis. However, the potential mechanism underlying the antiarthritic efficacy of Majoon Chobchini has not been elucidated so far. This study was aimed to explore the underlying molecular mechanism and scientifically validate the therapeutic ba...
Solanki, Preeti Putatunda, Chayanika Kumar, Anil Bhatia, Ravi Walia, Abhishek
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3 Biotech
Proteases are ubiquitous enzymes, having significant physiological roles in both synthesis and degradation. The use of microbial proteases in food fermentation is an age-old process, which is today being successfully employed in other industries with the advent of ‘omics’ era and innovations in genetic and protein engineering approaches. Proteases ...
Al-Joufi, Fakhria A. Aljarallah, Khalid M. Hagras, Soheir A. Al Hosiny, Ibrahim M. Salem‑Bekhit, Mounir M. Youssof, Abdullah M. E. Shakeel, Faiyaz
Published in
3 Biotech
Kumaran, Selvapravin Ngo, Anna Christina R. Schultes, Fabian Peter Josef Tischler, Dirk
Published in
3 Biotech
Shah, Abhishek Shah, Aarti Abhishek Nandakumar, Krishnadas Kumar, Avinash Pai, Aravinda Lobo, Richard
Published in
3 Biotech
Pharmacological treatment for BPH includes 5-α reductase inhibitors as Finasteride and Dutasteride as a monotherapy or in combination with antimuscarinic drugs, alpha-blockers, 5-phosphodiesterase inhibitor drugs. Androgen receptor inhibitors revealed several adverse events as decreased libido, erectile dysfunction, ejaculatory dysfunction, and gyn...
Lokesha, S. Ravi Kumar, Y. S. Sujan Ganapathy, P. S. Gaur, Prashant Arjun, H. M.
Published in
3 Biotech
Choline oxidase catalyzes the oxidation of choline to glycine betaine via betaine aldehyde in glycine betaine biosynthesis and betaine acts as an osmolyte. Choline oxidase has attracted a great deal of attention because of its wide application in clinical and its potential use in enzymatic betaine production. Therefore, the development of efficient...
Yusof, Tengku Yasmin Lian, Melissa Qianyue Ong, Eugene Boon Beng Teh, Aik-Hong
Published in
3 Biotech
Yeast cell death is triggered when essential nutrients such as potassium and lipid are limited but ammonium is in excess. When ammonium and glucose were maintained at 100% of the normal concentration while all the other essential nutrients in yeast nitrogen base (YNB) were reduced to 2%, yeast growth was halted by ammonium toxicity. Yeast started t...
