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A, Mamalis E, Koo M, Garcha William Murphy Rr, Isseroff J, Jagdeo
Published in
Journal of Biophotonics
Skin fibrosis, often referred to as skin scarring, is a significant international health problem with limited treatment options. The hallmarks of skin fibrosis are increased fibroblast proliferation, collagen production, and migration speed. Recently published clinical observations indicate that visible red light may improve skin fibrosis. In this ...
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A, Mamalis E, Koo Rr, Isseroff William Murphy J, Jagdeo
Published in
PLoS ONE
Background: Skin fibrosis is a significant medical problem that leads to a functional, aesthetic, and psychosocial impact on quality-of-life. Light-emitting diode-generated 633-nm red light (LED-RL) is part of the visible light spectrum that is not known to cause DNA damage and is considered a safe, non-invasive, inexpensive, and portable potential...
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Erik Ames Wd, Hallett William Murphy
Published in
Clinical & Experimental Immunology
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Kl, Alderson William Murphy
Published in
Adv Exp Med Biol: Crossroads Between Innate and Adaptive Immunity II
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Pa, Taylor Mj, Ehrhardt Cj, Lees A, Panoskaltsis-Mortari Am, Krieg Ah, Sharpe William Murphy Js, Serody H, Hemmi S, Akira
...
Published in
Blood
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R, Puliaev I, Puliaeva La, Welniak Ae, Ryan M, Haas William Murphy Cs, Via
Published in
Journal of Japan Society of Immunology & Allergology in Otolaryngology
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William Murphy
Published in
Blood
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A, Shanker Ad, Brooks Ca, Tristan Jw, Wine Pj, Elliott H, Yagita K, Takeda Mj, Smyth William Murphy Tj, Sayers
...
Published in
J Natl Cancer Inst
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D, Redelman La, Welniak D, Taub William Murphy
Published in
Immunology and Cell Biology
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K, Sun M, Li Tj, Sayers La, Welniak William Murphy
Published in
Blood
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M, Motarjemi Whd, Hallett M, Li William Murphy
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Cm, Sungur Yj, Tang-Feldman Ae, Zamora M, Alvarez C, Pomeroy William Murphy
Published in
Blood
Natural killer (NK) cells express inhibitory receptors with varied binding affinities to specific major histocompatibility complex class I (MHC-I) haplotypes. NK cells can be classified as licensed or unlicensed based on their ability or inability to bind MHC-I, respectively. The role of donor vs host MHC on their development after allogeneic hemat...
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K, Sun Hh, Hsiao M, Li Erik Ames M, Bouchlaka La, Welniak T, Hagino J, Jagdeo Cc, Pai M, Chen
...
Published in
The Journal of Immunology
Graft-versus-host disease (GVHD) is a major complication of allogeneic bone marrow transplantation. It has been previously reported that lung GVHD severity directly correlates with the expansion of donor Th17 cells in the absence of IFN-γ. However, the consequence of Th17-associated lung GVHD in the presence of IFN-γ has not been well characterized...
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Erik Ames William Murphy
Published in
Transplantation Journal
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Rj, Canter Sk, Grossenbacher Erik Ames William Murphy
Published in
Journal of Gastrointestinal Oncology
The cancer stem cell (CSC) hypothesis postulates that a sub-population of quiescent cells exist within tumors which are resistant to conventional cytotoxic/anti-proliferative therapies. It is these CSCs which then seed tumor relapse, even in cases of apparent complete response to systemic therapy. Therefore, therapies, such as immunotherapy, which ...
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Cm, Minnar William Murphy
Published in
Human Vaccines & Immunotherapeutics
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R, Flynn Jl, Allen L, Luznik Kp, Macdonald K, Paz Ka, Alexander A, Vulic J, Du A, Panoskaltsis-Mortari Pa, Taylor
...
Published in
Blood
Novel therapies for chronic graft-versus-host disease (cGVHD) are needed. Aberrant B-cell activation has been demonstrated in mice and humans with cGVHD. Having previously found that human cGVHD B cells are activated and primed for survival, we sought to further evaluate the role of the spleen tyrosine kinase (Syk) in cGVHD in multiple murine model...
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M, Boeckh William Murphy Ks, Peggs
Published in
Biology of Blood and Marrow Transplantation
The 2015 Tandem American Society for Blood and Marrow Transplantation/Center for International Blood and Marrow Transplant Meetings provide an opportunity to review the current status and future perspectives on therapy for cytomegalovirus (CMV) infection in the setting of hematopoietic stem cell transplantation (HSCT). After many years during which...
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M, Boeckh William Murphy Ks, Peggs
Published in
Biology of Blood and Marrow Transplantation
The 2015 Tandem American Society for Blood and Marrow Transplantation/Center for International Blood and Marrow Transplant Meetings provide an opportunity to review the current status and future perspectives on therapy for cytomegalovirus (CMV) infection in the setting of hematopoietic stem cell transplantation (HSCT). After many years during which...
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Cc, Pai Hh, Hsiao K, Sun M, Chen T, Hagino J, Tellez C, Mall Br, Blazar A, Monjazeb M, Abedi
...
Published in
Biology of Blood and Marrow Transplantation
Bortezomib, a proteasome inhibitor capable of direct antitumor effects, has been shown to prevent acute graft-versus-host disease (GVHD) when administered in a short course immediately after bone marrow transplantation (BMT) in mice. However, when bortezomib is given continuously, CD4(+) T cell-mediated gastrointestinal tract damage increases GVHD ...
