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Sa, Woller Sb, Ravula Fc, Tucci G, Beaton M, Corr Rivkah Isseroff Am, Soulika Marianne Chigbrow Ka, Eddinger Tl, Yaksh
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Published in
Brain Behavior and Immunity
Objective: Pain resulting from local tissue injury or inflammation typically resolves with time. Frequently, however, this pain may unexpectedly persist, becoming a pathological chronic state. Increasingly, the innate and adaptive immune systems are being implicated in the initiation and maintenance of these persistent conditions. In particular, To...
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Andrew Mamalis E, Koo M, Garcha Wj, Murphy Rivkah Isseroff Jared Jagdeo
Published in
Journal of Biophotonics
Skin fibrosis, often referred to as skin scarring, is a significant international health problem with limited treatment options. The hallmarks of skin fibrosis are increased fibroblast proliferation, collagen production, and migration speed. Recently published clinical observations indicate that visible red light may improve skin fibrosis. In this ...
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Andrew Mamalis E, Koo Rivkah Isseroff W, Murphy Jared Jagdeo
Published in
PLoS ONE
Background: Skin fibrosis is a significant medical problem that leads to a functional, aesthetic, and psychosocial impact on quality-of-life. Light-emitting diode-generated 633-nm red light (LED-RL) is part of the visible light spectrum that is not known to cause DNA damage and is considered a safe, non-invasive, inexpensive, and portable potential...
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Db, Eisen Cw, Schupp Rivkah Isseroff Oa, Ibrahimi L, Ledo Aw, Armstrong
Published in
Current Topics in Medicinal Chemistry
Background: Little is known about the impacts of class attendance and learning preferences on academic performance in dermatology.
Objectives: This study was designed to examine the effects of medical student class attendance and learning preferences on students' academic performance in an introductory dermatology course.
Methods: A total of ...
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Hsin-Ya Yang Tina La Rivkah Isseroff
Published in
Journal of Visualized Experiments
The physiological electric field serves specific biological functions, such as directing cell migration in embryo development, neuronal outgrowth and epithelial wound healing. Applying a direct current electric field to cultured cells in vitro induces directional cell migration, or galvanotaxis. The 2-dimensional galvanotaxis method we demonstrate ...
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Hsin-Ya Yang Tina La Z, Gurenko P, Steenhuis W, Liu Rivkah Isseroff
Published in
Journal of Cellular Physiology
Murine keratinocyte culture from neonatal skin is an important tool for studying the functional role of specific genes in epithelial biology. However, when the transgenic animal is only available in a geographically distant local, obtaining viable keratinocytes can be problematic. A method for transferring the isolated murine skin from collaboratin...
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Raja Sivamani B, Shi E, Griffiths Sm, Vu Ha, Lev-Tov S, Dahle Marianne Chigbrow Tina La C, Mashburn Thomas Peavy
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Published in
Journal of Investigative Dermatology
Keratinocyte migration is critical for wound re-epithelialization. Previous studies showed that epinephrine activates the beta2-adrenergic receptor (B2AR), impairing keratinocyte migration. Here, we investigated the keratinocyte catecholamine synthetic pathway in response to acute trauma. Cultured keratinocytes were scratch wounded and expression l...
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I, Pastar O, Stojadinovic Nc, Yin H, Ramirez Ag, Nusbaum A, Sawaya Sb, Patel L, Khalid Rivkah Isseroff M, Tomic-Canic
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Published in
Advances in Wound Care
Significance: Keratinocytes, a major cellular component of the epidermis, are responsible for restoring the epidermis after injury through a process termed epithelialization. This review will focus on the pivotal role of keratinocytes in epithelialization, including cellular processes and mechanisms of their regulation during re-epithelialization, ...
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J, Olazagasti As, Wang Rivkah Isseroff
Published in
JAMA Dermatology
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Hsin-Ya Yang Rp, Charles E, Hummler Dl, Baines Rivkah Isseroff
Published in
Journal of Cell Science
Cellular directional migration in an electric field (galvanotaxis) is one of the mechanisms guiding cell movement in embryogenesis and in skin epidermal repair. The epithelial sodium channel (ENaC), in addition to its function of regulating sodium transport in kidney, has recently been found to modulate cell locomotory speed. Here we tested whether...
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H, Lev-Tov C, Li S, Dahle Rivkah Isseroff
Published in
Trials
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Rivkah Isseroff Se, Dahle
Published in
Advances in Wound Care
Background
Healing chronic wounds is an ongoing challenge for clinicians and poses a serious public health burden. Electrical stimulation (ES), broadly defined as the application of electrical current via electrodes placed on the skin adjacent to or directly within the wound, has been proposed as a therapeutic modality over a century ago, and rece...
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Mr, Dasu Rivkah Isseroff
Published in
Journal of Investigative Dermatology
Toll-like receptors (TLRs) are considered to be the first responders in the defense against invading pathogens. TLR engagement by ligands triggers inflammatory responses in injury and trauma, and thus can impair or contribute to the healing process, depending on TLRs expression pattern, cellular localization, signaling, and deployment of inflammat...
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M R, Dasu S, Ramirez Rivkah Isseroff
Published in
Clin Sci (Lond)
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A E, Rizzo L A, Beckett B S, Baier Rivkah Isseroff
Published in
Skin Research and Technology
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W, Liu D K, Hsu H Y, Chen R Y, Yang K L, Carraway Rivkah Isseroff F T, Liu
Published in
Journal of Investigative Dermatology Symposium Proceedings
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Raja Sivamani M P, Schwartz K S, Anseth Rivkah Isseroff
Published in
The FASEB Journal
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P, Steenhuis R E, Huntley Z, Gurenko L, Yin B A, Dale N, Fazel Rivkah Isseroff
Published in
Journal of Advanced Medical and Dental Sciences Research
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S D, Fitzmaurice Raja Sivamani Rivkah Isseroff
Published in
Skin Pharmacology and Physiology
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Y C, Liu D J, Margolis Rivkah Isseroff
Published in
Journal of Investigative Dermatology Symposium Proceedings