Raja Sivamani

The use of botanical agents in the treatment of acne

Published in Current Reports in Dermatology

Evaluating clinical trial design: systematic review of randomized vehicle-controlled trials for determining efficacy of ...

Published in Archives of Dermatological Research

Determined efficacies of benzoyl peroxide may be affected by study design, implementation, and vehicle effects. We sought to elucidate areas that may allow improvement in determining accurate treatment efficacies by determining rates of active treatment and vehicle responders in randomized controlled trials assessing the efficacy of topical benzoyl...

The use of facial modeling and analysis to objectively quantify facial redness.

Published in Journal of Cosmetic Dermatology

Set-back versus buried vertical mattress suturing: results of a randomized blinded trial.

Published in Journal of the American Academy of Dermatology

Squamous cell carcinoma in the setting of chronic hidradenitis suppurativa; report of a patient and update of the litera...

Published in Dermatology online journal

Squamous cell carcinoma (SCC) developing in chronic hidradenitis suppurativa (HS) is rare, but failing to recognize the condition may have significant consequences. Dermatologists must be aware of the potential for malignant transformation and should have a low threshold for biopsy when clinical presentation is atypical. Herein we describe a 64-yea...

Antioxidant therapies for wound healing: a clinical guide to currently commercially available products.

Published in Skin Pharmacology and Physiology

Many facets of wound healing under redox control require a delicate balance between oxidative stress and antioxidants. While the normal physiology of wound healing depends on low levels of reactive oxygen species and oxidative stress, an overexposure to oxidative stress leads to impaired wound healing. Antioxidants are postulated to help control wo...

Advice for fourth year medical students beginning the dermatology residency application process: Perspectives from inter...

Published in Dermatology online journal

Shedding light on sunscreens and their labels: Testing policies need to match actual use.

Published in American Journal of Preventive Medicine

Comparative prevalence of complementary and alternative medicine use among outpatients in dermatology and primary care c...

Published in JAMA Dermatology

Polyphenols as novel treatment options for dermatological diseases: A systematic review of clinical trials.

Published in Journal of Dermatological Treatment

Cedarwood Oil as Complementary Treatment in Refractory Acne.

Published in The Journal of Alternative and Complementary Medicine

Acne vulgaris is a widely prevalent chronic skin disease. Although multiple treatments are available, acne can sometimes be refractory to these treatments. The use of alternative medical therapies has increased within dermatology and for acne. This case report describes a patient in whom the addition of cedarwood oil was helpful in controlling acne...

Fruits are rich in antioxidants and ripe for topical therapy.

Published in Journal of Dermatological Treatment

The association of the sebum excretion rate with melasma, erythematotelangiectatic rosacea, and rhytides.

Published in Dermatology online journal

Objective volumetric grading of postacne scarring.

Published in Journal of the American Academy of Dermatology

Eicosanoids and Keratinocytes in Wound Healing.

Published in Advances in Wound Care

Significance: Eicosanoids are biologically active lipid mediators derived from arachidonic acid that are important in injury and inflammatory responses. Cyclooxygenase-1 and cyclooxygenase-2 mediate the production of prostanoids, whereas 5-lipoxygenase mediates the production of leukotrienes and hydroxyeicosatetraenoic acids. These lipid mediators ...

Role of sebaceous glands in inflammatory dermatoses.

Published in Journal of the American Academy of Dermatology

Skin is an important interface between the host and its environment. Inflammatory dermatoses often have disrupted skin barrier function, rendering patients more susceptible to allergenic triggers leading to an exaggerated immune response. The skin surface lipid film, an important component of the skin barrier, comprises a mixture of keratinocyte an...

Alopecia as the Presenting Symptom of Syphilis.

Published in Dermatology online journal

Alopecia can be one of the many symptoms of secondary syphilis and the clinical presentations include essential syphilitic alopecia or symptomatic syphilitic alopecia. In this report, we present a case of a patient with essential syphilitic alopecia whose sole presenting symptom of syphilis was alopecia. Despite an initial negative rapid plasma rea...

The use of botanically derived agents for hyperpigmentation: a systematic review.

Published in Journal of the American Academy of Dermatology

Does wound eversion improve cosmetic outcome?: Results of a randomized, split-scar, comparative trial.

Published in Journal of the American Academy of Dermatology