Natsuko Nomura

Novel anti-glioblastoma agents and therapeutic combinations identified from a collection of FDA approved drugs.

Published in Journal of Translational Medicine

In silico modeling predicts drug sensitivity of patient-derived cancer cells.

Published in Journal of Translational Medicine

High-efficiency liposomal encapsulation of a tyrosine kinase inhibitor leads to improved in vivo toxicity and tumor resp...

Published in International Journal of Nanomedicine

Staurosporine (STS) is a potent pan-kinase inhibitor with marked activity against several chemotherapy-resistant tumor types in vitro. The translational progress of this compound has been hindered by poor pharmacokinetics and toxicity. We sought to determine whether liposomal encapsulation of STS would enhance antitumor efficacy and reduce toxicity...

Effect of the JAK2/STAT3 inhibitor SAR317461 on human glioblastoma tumorspheres.

Published in Journal of Translational Medicine

Hyaluronan expression in primary and secondary brain tumors.

Published in Annals of Translational Medicine

Prostate specific membrane antigen (PSMA) expression in primary gliomas and breast cancer brain metastases.

Published in Cancer Cell International

In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells.

Published in British Journal of Cancer