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Linda Narhi

Institution: AIMS
Research topics:
Proces Protein Structure And Function Protein-Based Therapeutics
United States
https://www.mysciencework.com/profile/linda.narhi
  • 1 published article

Physical Characterization and In Vitro Biological Impact of Highly Aggregated Antibodies Separated into Size-Enriched Po...

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Srivalli Telikepalli Heather E. Shinogle Prem S. Thapa Jae Hyun Kim Meghana Deshpande Vibha Jawa C. Russell Middaugh Linda Narhi Marisa K. Joubert David B. Volkin ...

Published in Journal of Pharmaceutical Sciences

An IgG2 monoclonal antibody (mAb) solution was subjected to stirring, generating high concentrations of nanometer and subvisible particles, which were then successfully size-enriched into different size bins by low-speed centrifugation or a combination of gravitational sedimentation and fluorescence-activated cell sorting (FACS). The size-fractiona...

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