Identification of small ubiquitin-like modifier substrates with diverse functions using the Xenopus egg extract system.
Published in Molecular & Cellular Proteomics
Post-translational modification by SUMO is a highly conserved pathway in eukaryotes that plays very important regulatory roles in many cellular processes. Deregulation of the SUMO pathway contributes to the development and progression of many diseases including cancer. Therefore, identifying additional SUMO substrates and studying how their cellula...
