Image-based siRNA screen to identify kinases regulating Weibel-Palade body size control using electroporation.
Published in Journal of Genetics and Genomics
Published in Immunology
Published in Scientific Reports
Published in Nature Communications
Published in Cytometry Part A
Published in Cell Reports
Published in Biochemistry
Published in Encyclopedia of Cell Biology
Published in Nature
Cell division requires the precise coordination of chromosome segregation and cytokinesis. This coordination is achieved by the recruitment of an actomyosin regulator, Ect2, to overlapping microtubules at the centre of the elongating anaphase spindle. Ect2 then signals to the overlying cortex to promote the assembly and constriction of an actomyosi...