Publications - Hiroko Matsui - Page 1

Effective filtering strategies to improve data quality from population-based whole exome sequencing studies.

Ar, Carson Erin N. Smith Hiroko Matsui Sk, Brækkan K, Jepsen Jb, Hansen Kelly A. Frazer

Published in BMC Bioinformatics

Evaluation of ultra-deep targeted sequencing for personalized breast cancer care.

O, Harismendy Rb, Schwab H, Alakus Se, Yost Hiroko Matsui F, Hasteh Am, Wallace Hl, Park L, Madlensky B, Parker ...

Published in Breast Cancer Research

Mutascope: sensitive detection of somatic mutations from deep amplicon sequencing.

Kelly A. Frazer O, Harismendy Se, Yost H, Alakus Hiroko Matsui Rb, Schwab K, Jepsen

Published in Bioinformatics

Genetic and epigenetic profiling of CLL disease progression reveals limited somatic evolution and suggests a relationshi...

Erin N. Smith Em, Ghia Cm, Deboever Lz, Rassenti K, Jepsen Ka, Yoon Hiroko Matsui S, Rozenzhak H, Alakus Pj, Shepard ...

Published in Blood Cancer Journal

We examined genetic and epigenetic changes that occur during disease progression from indolent to aggressive forms of chronic lymphocytic leukemia (CLL) using serial samples from 27 patients. Analysis of DNA mutations grouped the leukemia cases into three categories: evolving (26%), expanding (26%) and static (47%). Thus, approximately three-quarte...