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J, Kwak Emanual Maverakis
Published in
Dermatology online journal
A 13-year-old boy presented to the dermatology clinic for treatment of a congenital ichthyosis with a history of generalized erythroderma and trauma related blistering at the time of birth. At the time of presentation he was noted to have red corrugated hyperkeratotic plaques involving the joint flexures, dorsal hands, and neck. Epidermolytic hyper...
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My, Cheng A, Sukhov H, Sultani K, Kim Emanual Maverakis
Published in
JAMA Dermatology
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A, Mitra Ji, Luna Ai, Marusina A, Merleev S, Kundu-Raychaudhuri D, Fiorentino Sp, Raychaudhuri Emanual Maverakis
Published in
Journal of Investigative Dermatology
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Mn, Bouchlaka Gd, Sckisel M, Chen A, Mirsoian Ae, Zamora Emanual Maverakis De, Wilkins Kl, Alderson Hh, Hsiao Jm, Weiss
...
Published in
Journal of Experimental Medicine
Cancer commonly occurs in the elderly and immunotherapy (IT) is being increasingly applied to this population. However, the majority of preclinical mouse tumor models assessing potential efficacy and toxicities of therapeutics use young mice. We assessed the impact of age on responses to systemic immune stimulation. In contrast to young mice, syste...
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V, Sharon B, Burrall F, Patel Y, He T, Konia Ib, Villalobos Emanual Maverakis
Published in
Dermatology online journal
A 13-year old girl was admitted to the University of California Davis Medical Center for evaluation and treatment of cutaneous bullae and ulcerations over her lower extremities that were refractory to antibiotic therapy and incision and drainage. Her disease continued to worsen with the appearance of multiple new bullae and the progression of old o...
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Sk, Raychaudhuri Emanual Maverakis Sp, Raychaudhuri
Published in
Autoimmunity Reviews
Psoriasis is a chronic inflammatory multi organ disease with well characterized pathology occurring in the skin and often the joints. Although the disease has many characteristic and even pathognomonic features, no established diagnostic criteria exist for cutaneous psoriasis and there is no unified classification for the clinical spectrum of the d...
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Emanual Maverakis Y, Miyamura Mp, Bowen G, Correa Y, Ono H, Goodarzi
Published in
Journal of Autoimmunity
Ultraviolet (UV) light is intricately linked to the functional status of the cutaneous immune system. In susceptible individuals, UV radiation can ignite pathogenic inflammatory pathways leading to allergy or autoimmunity. In others, this same UV radiation can be used as a phototherapy to suppress pathogenic cutaneous immune responses. These vastly...
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Emanual Maverakis P, Van Den Elzen Ee, Sercarz
Published in
Journal of Autoimmunity
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M, Rudolph K, Hebel Y, Miyamura Emanual Maverakis Mc, Brunner-Weinzierl
Published in
The Journal of Immunology
CTLA-4 is known as a central inhibitor of T cell responses. It terminates T cell activation and proliferation and induces resistance against activation induced cell death. However, its impact on memory formation of adaptive immune responses is still unknown. In this study, we demonstrate that although anti-CTLA-4 mAb treatment during primary immuni...
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H, Goodarzi Rk, Sivamani Ms, Garcia Ln, Wehrli H, Craven Y, Ono Emanual Maverakis
Published in
Advances in Wound Care
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Rk, Sivamani Br, Ma Ln, Wehrli Emanual Maverakis
Published in
Advances in Wound Care
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Emanual Maverakis J, Beech Db, Stevens A, Ametani L, Brossay P, Van Den Elzen R, Mendoza Q, Thai Lh, Macias D, Ethell
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Published in
Proceedings of the National Academy of Sciences
It is not clear why the N-terminal autoantigenic determinant of myelin basic protein (MBP), Ac1-9, is dominant in the B1O.PL (H-2(u)) mouse, given its weak I-A(u)-MHC binding affinity. Similarly, how do high-affinity T cells specific for this determinant avoid negative selection? Because the MBP:1-9 sequence is embryonically expressed uniquely in t...
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D, Park Ka, Brune A, Mitra Ai, Marusina Emanual Maverakis Cb, Lebrilla
Published in
Molecular & Cellular Proteomics
Changes in cell surface glycosylation occur during the development and differentiation of cells and have been widely correlated with the progression of several diseases. Because of their structural diversity and sensitivity to intra- and extracellular conditions, glycans are an indispensable tool for analyzing cellular transformations. Glycans pres...
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E, Loh Ma, Fung Emanual Maverakis
Published in
Archives of Dermatology