RNA modeling using Gibbs sampling and stochastic context free grammars.
Published in International Conference on Intelligent Systems for Molecular Biology
A new method of discovering the common secondary structure of a family of homologous RNA sequences using Gibbs sampling and stochastic context-free grammars is proposed. Given an unaligned set of sequences, a Gibbs sampling step simultaneously estimates the secondary structure of each sequence and a set of statistical parameters describing the comm...