HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components a...
Published in Development
The nephron is a highly specialised segmented structure that provides essential filtration and resorption renal functions. It arises by formation of a polarised renal vesicle that differentiates into a comma-shaped body and then a regionalised S-shaped body (SSB), with the main prospective segments mapped to discrete domains. The regulatory circuit...