Yao-Hui Sun
Institution:
zhaolab-ucdavis, dermatology-ucdavis
Davis, CA, United States
https://www.mysciencework.com/profile/yao.hui.sun
Summary
Published articles Show More
Airway epithelial wounds in rhesus monkey generate ionic currents that guide cell migration to promote healing.
Published in Journal of Applied Physiology
Damage to the respiratory epithelium is one of the most critical steps to many life-threatening diseases, such as acute respiratory distress syndrome and chronic obstructive pulmonary disease. The mechanisms underlying repair of the damaged epithelium have not yet been fully elucidated. Here we provide experimental evidence suggesting a novel mecha...
cAMP and cGMP Play an Essential Role in Galvanotaxis of Cell Fragments.
Published in Journal of Cellular Physiology
Cell fragments devoid of the nucleus and major organelles are found in physiology and pathology, for example platelets derived from megakaryocytes, and cell fragments from white blood cells and glioma cells. Platelets exhibit active chemotaxis. Fragments from white blood cells display chemotaxis, phagocytosis, and bactericidal functions. Signaling ...
E-cadherin plays an essential role in collective directional migration of large epithelial sheets.
...Published in Cellular and Molecular Life Sciences
In wound healing and development, large epithelial sheets migrate collectively, in defined directions, and maintain tight cell-cell adhesion. This type of movement ensures an essential function of epithelia, a barrier, which is lost when cells lose connection and move in isolation. Unless wounded, epithelial sheets in cultures normally do not have ...
