Tina La
Staff Research Associate
Summary
Published articles Show More
Utilizing custom-designed galvanotaxis chambers to study directional migration of prostate cells.
Published in Journal of Visualized Experiments
The physiological electric field serves specific biological functions, such as directing cell migration in embryo development, neuronal outgrowth and epithelial wound healing. Applying a direct current electric field to cultured cells in vitro induces directional cell migration, or galvanotaxis. The 2-dimensional galvanotaxis method we demonstrate ...
Recovery and Cultivation of Keratinocytes From Shipped Mouse Skin.
Published in Journal of Cellular Physiology
Murine keratinocyte culture from neonatal skin is an important tool for studying the functional role of specific genes in epithelial biology. However, when the transgenic animal is only available in a geographically distant local, obtaining viable keratinocytes can be problematic. A method for transferring the isolated murine skin from collaboratin...
Acute wounding alters the beta2-adrenergic signaling and catecholamine synthetic pathways in keratinocytes.
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Published in Journal of Investigative Dermatology
Keratinocyte migration is critical for wound re-epithelialization. Previous studies showed that epinephrine activates the beta2-adrenergic receptor (B2AR), impairing keratinocyte migration. Here, we investigated the keratinocyte catecholamine synthetic pathway in response to acute trauma. Cultured keratinocytes were scratch wounded and expression l...