I am a stem cell biologist working at the interface of R&D and Marketing for Fluidigm. My passion for science, research and innovation led me to enter the field of single-cell biology and to work for Fluidigm. Along the way, I co-founded AIMS and a crowdfunding platform dedicated to fund projects in healthcare, cleantech and education industries. I am also an advisor for the lifescience and big data space and a co-founder of OneTraction Accelerator where I advise and mentor start-ups. ...
Regulation of Pax3 by Proteasomal Degradation of Monoubiquitinated Protein in Skeletal Muscle Progenitors
Published in Cell
SUMMARY Pax3 and Pax7 play distinct but overlapping roles in developmental and postnatal myogene-sis. The mechanisms involved in the differential regulation of these highly homologous proteins are unknown. We present evidence that Pax3, but not Pax7, is regulated by ubiquitination and proteasomal degradation during adult muscle stem cell activation...
Published in Cell Stem Cell
These authors contributed equally to this work *Correspondence: [email protected] DOI 10.1016/j.stem.2012.01.017 SUMMARY Pax3, a key myogenic regulator, is transiently ex-pressed during activation of adult muscle stem cells, or satellite cells (SCs), and is also expressed in a subset of quiescent SCs (QSCs), but only in specific muscles. The mecha...
Collaboration Manager Since May 2013
Fluidigm Corporation (South San Francisco US)
Work at the interface of R&D and Marketing. Manage collaboration to create traction for new applications and new platform. Develop performance specs for new products based on market analysis
Doctorate September 1997 - January 2001
Université Denis Diderot-Paris 7 (Paris FR)
Study angiogenesis during the development and during cancer