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Published in Pharmacological Research
Despite the discovery of tyrosine kinase inhibitors (TKIs) for the treatment of breakpoint cluster region-Abelson (BCR-ABL) + cancer types, patients with chronic myeloid leukemia (CML) treated with TKIs develop resistance and severe adverse effects. Combination treatment, especially with a histone deacetylase (HDAC) 6 inhibitor (HDAC6i), appears to...
In vitro and in vivo study of nanoparticle toxicity.
Toxicity study of nanoparticles on in vitro and in vivo models.
SmartNanoTox project
Preclinical evaluation of a series of anti-caner 4-hydroxybenzoic acid derivatives as histone deacetylase inhibitors