Differentiation team
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Sébastien Chateauvieux
Discipline:
Biology
Summary
Published articles Show More
Inflammation regulates long non-coding RNA-PTTG1-1:1 in myeloid leukemia.
...Published in Haematologica
No abstract available
Sphingolipid-mediated inflammatory signaling leading to autophagy inhibition converts erythropoiesis to myelopoiesis in ...
Published in Cell Death and Differentiation
Elevated levels of the pro-inflammatory cytokine tumor necrosis factor-α (TNFα) inhibit erythropoiesis and cause anemia in patients with cancer and chronic inflammatory diseases. TNFα is also a potent activator of the sphingomyelinase (SMase)/ ceramide pathway leading to ceramide synthesis and regulating cell differentiation, proliferation, apoptos...
Early downregulation of Mcl-1 regulates apoptosis triggered by cardiac glycoside UNBS1450
Published in Cell Death and Disease
Cardiac glycosides (CGs), prescribed to treat cardiovascular alterations, display potent anti-cancer activities. Despite their well-established target, the sodium/potassium (Na + /K +)-ATPase, downstream mechanisms remain poorly elucidated. UNBS1450 is a hemi-synthetic cardenolide derived from 2″-oxovorusharin extracted from the plant Calotropis pr...
