Dr. Santosh Kesari is Professor of Neurosciences at UC San Diego School of Medicine, and Director of Neuro-oncology at Moores UCSD Cancer Center. His research investigates the biology of gliomas with the aim of developing new therapeutics for patients with brain tumors. He has a long-standing interest in neural development and cancer stem cells and is focusing on their role in the formation of brain tumors and resistance to treatments.
Santosh Kesari
Director, Neuro-Oncology, Professor
Institution:
Kesari Lab
La Jolla, CA, United States
https://www.mysciencework.com/profile/santosh.kesari
Summary
Published articles Show More
Cerebral syphilitic gumma: a case report and review of the literature.
Published in Neurological Sciences
A 45-year-old male presented with subacute onset of a right-sided hemiparesis, right homonymous hemianopsia, and slurred speech. The brain imaging revealed two separate intraparenchymal enhancing lesions. The cerebrospinal fluid rapid plasma reagin and venereal disease research laboratory test were positive and consistent with syphilitic gumma, and...
Targeting and depletion of circulating leukocytes and cancer cells by lipophilic antibody-modified erythrocytes.
Published in Journal of Controlled Release
There is a great interest in targeting and selective ablation of populations of circulating cells for research or therapeutic purposes. Red blood cells (RBCs) are readily available and fully biocompatible long-circulating intravascular carriers (natural life is 120days) that are amenable to chemical modifications, drug loading and reinjection. Here...
Understanding the origins of gliomas and developing novel therapies: cerebrospinal fluid and subventricular zone interpl...
Published in Seminars in Oncology
Glioblastoma multiforme (GBM), the most common malignant primary brain tumor in adults, carries a poor prognosis, with median survival generally less than 1 year. Although initial therapy often eradicates the bulk of the tumor, disease recurrence, usually within 2 cm of the original tumor, is almost inevitable. This may be due to a failure of curre...
