Pamela Yao
Summary
Published articles Show More
Interferon-gamma inhibits healing post scald burn injury.
Published in Wound Repair and Regeneration
Impaired healing after severe burns remains a reason for prolonged hospitalization, opportunistic infections, and debilitating scarring. Interferon-gamma (IFN-γ) is an important immune regulator that has been shown to inhibit collagen synthesis by fibroblasts, resulting in delayed healing in incision wounds. To determine whether IFN-γ plays similar...
Therapeutic depletion of monocyte-derived cells protects from long-term axonal loss in experimental autoimmune encephalo...
Published in Journal of Neuroimmunology
Studies in multiple sclerosis and its animal model experimental autoimmune encephalomyelitis (EAE) suggest that peripheral monocyte-derived cells (MDCs) are instrumental for disease initiation. MDCs, however, are plastic, and may exert various functions once in the central nervous system (CNS) for prolonged periods. Furthermore, the long-term effec...