Functional Deficiencies in Fragile X Neurons Derived from Human Embryonic Stem Cells

Published in Journal of Neuroscience

Molecular Mechanisms Regulating Impaired Neurogenesis of Fragile X Syndrome Human Embryonic Stem Cells

Published in Stem Cells and Development

Human embryonic stem cells carrying an unbalanced translocation demonstrate impaired differentiation into trophoblasts: ...

Published in MHR Basic science of reproductive medicine

Carriers of the balanced translocation t(11;22), the most common reciprocal translocation in humans, are at high risk of creating gametes with unbalanced translocation, leading to repeated miscarriages. Current research models for studying translocated embryos and the biological basis for their implantation failure are limited. The aim of this stud...