PhD
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Marion Orsini
Discipline:
Biology
Luxembourg, Luxembourg
https://www.mysciencework.com/profile/marion.orsini
Summary
Published articles Show More
Inflammation regulates long non-coding RNA-PTTG1-1:1 in myeloid leukemia.
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Published in Haematologica
No abstract available
Sphingolipid-mediated inflammatory signaling leading to autophagy inhibition converts erythropoiesis to myelopoiesis in ...
Published in Cell Death and Differentiation
Elevated levels of the pro-inflammatory cytokine tumor necrosis factor-α (TNFα) inhibit erythropoiesis and cause anemia in patients with cancer and chronic inflammatory diseases. TNFα is also a potent activator of the sphingomyelinase (SMase)/ ceramide pathway leading to ceramide synthesis and regulating cell differentiation, proliferation, apoptos...
Polyphenol tri-vanillic ester 13c inhibits P-JAK2V617F and Bcr–Abl oncokinase expression in correlation with STAT3/STAT5...
Published in Cancer Letters
Constitutive activity of kinases has been reported in many types of cancers, so that inhibition of "onco-kinases" became a validated anti-cancer strategy. We found that the polyphenol 13c, a tri-vanillate derivative, inhibited kinase phosphorylation in leukemia cells. P-JAK2, P-Src and P-PI3Kp85 inhibition occurred independently of phosphatase invo...
