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Marie-Agnès Sari
Directeur de l'unité, CNRS/Paris 5, UMR 8601, Chimie et Biochimie Pharmacologiques et Toxicologiques
Institution:
USPC - SET - SVS
Summary
Published articles Show More
Recombinant overexpression of camel hepcidin cDNA in Pichia pastoris: purification and characterization of the polyHis-t...
...Published in Journal of Molecular Recognition
Hepcidin, a liver‐expressed antimicrobial peptide, has been demonstrated to act as an iron regulatory hormone as well as to exert a wide spectrum of antimicrobial activity. The aim of this work was the expression, as secreted peptide, purification, and characterization of a new recombinant polyHis‐tagged camel hepcidin (HepcD‐His) in yeast Pichia p...
Insights into the interaction of high potency inhibitor IRC-083864 with phosphatase CDC25
...Published in Arterial’naya Gipertenziya (Arterial Hypertension)
CDC25 phosphatases play a crucial role in cell cycle regulation. They have been found to be over‐expressed in various human tumours and to be valuable targets for cancer treatment. Here, we report the first model of binding of the most potent CDC25 inhibitor to date, the bis‐quinone IRC‐083864, into CDC25B obtained by combining molecular modeling a...
The Andromonoecious Sex Determination Gene Predates the Separation of Cucumis and Citrullus Genera
...Published in PLoS ONE
Understanding the evolution of sex determination in plants requires the cloning and the characterization of sex determination genes. Monoecy is characterized by the presence of both male and female flowers on the same plant. Andromonoecy is characterized by plants carrying both male and bisexual flowers. In watermelon, the transition between these ...
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Experience
Directeur de l'unité Since 2004
université Paris Descartes
CNRS/Paris 5, UMR 8601, Chimie et Biochimie Pharmacologiques et Toxicologiques; Centre Interdisciplinaire Chimie Biologie - Paris (CICB-Paris); Faculté des Sciences Fondamentales et Biomédicales
Education
Ph.D. 1995 - 1998
Université Pierre et Marie Curie - Paris 6 (Paris FR)
Pharmacology
