Marianne Chigbrow
Laboratory Manager; Staff Research Associate
Institution:
Isseroff Lab, dermatology-ucdavis
Davis, CA, United States
https://www.mysciencework.com/profile/marianne.chigbrow
Summary
Published articles Show More
Systemic TAK-242 prevents intrathecal LPS evoked hyperalgesia in male, but not female mice and prevents delayed allodyni...
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Published in Brain Behavior and Immunity
Objective: Pain resulting from local tissue injury or inflammation typically resolves with time. Frequently, however, this pain may unexpectedly persist, becoming a pathological chronic state. Increasingly, the innate and adaptive immune systems are being implicated in the initiation and maintenance of these persistent conditions. In particular, To...
Acute wounding alters the beta2-adrenergic signaling and catecholamine synthetic pathways in keratinocytes.
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Published in Journal of Investigative Dermatology
Keratinocyte migration is critical for wound re-epithelialization. Previous studies showed that epinephrine activates the beta2-adrenergic receptor (B2AR), impairing keratinocyte migration. Here, we investigated the keratinocyte catecholamine synthetic pathway in response to acute trauma. Cultured keratinocytes were scratch wounded and expression l...
