Malik Bisserier

Intra-tracheal gene delivery of aerosolized SERCA2a to the lung suppresses ventricular arrhythmias in a model of pulmona...

Strauss, Benjamin Sassi, Yassine Bueno-Beti, Carlos Ilkan, Zeki Raad, Nour Cacheux, Marine Malik Bisserier Turnbull, Irene C. Kohlbrenner, Erik Hajjar, Roger J. ...

Published in Journal of Molecular and Cellular Cardiology

Background Pulmonary arterial hypertension (PAH) results in right ventricular (RV) failure, electro-mechanical dysfunction and heightened risk of sudden cardiac death (SCD), although exact mechanisms and predisposing factors remain unclear. Because impaired chronotropic response to exercise is a strong predictor of early mortality in patients with...

Mechanisms of resistance to EZH2 inhibitors in diffuse large B-cell lymphomas

Malik Bisserier Wajapeyee, Narendra

Published in Blood

Resistance to targeted therapies has become increasingly prevalent. We noted that resistance to different targeted therapies occurs by largely common mechanisms. In this study, we used this information for identifying the mechanisms of resistance to enhancer of zeste homolog 2 (EZH2) inhibitors in diffuse large B-cell lymphoma (DLBCL) harboring EZH...

Multifunctional Mitochondrial Epac1 Controls Myocardial Cell Death.

Fazal, Loubina Laudette, Marion Paula-Gomes, Sílvia Pons, Sandrine Conte, Caroline Tortosa, Florence Sicard, Pierre Sainte-Marie, Yannis Malik Bisserier Lairez, Olivier ...

Published in Circulation Research

Although the second messenger cyclic AMP (cAMP) is physiologically beneficial in the heart, it largely contributes to cardiac disease progression when dysregulated. Current evidence suggests that cAMP is produced within mitochondria. However, mitochondrial cAMP signaling and its involvement in cardiac pathophysiology are far from being understood.

Postdoctoral Researcher, Mount sinai School of Medicine (New York)

Summary

Published articles Show More

Intra-tracheal gene delivery of aerosolized SERCA2a to the lung suppresses ventricular arrhythmias in a model of pulmona...

Mechanisms of resistance to EZH2 inhibitors in diffuse large B-cell lymphomas

Multifunctional Mitochondrial Epac1 Controls Myocardial Cell Death.

Experience

Postdoctoral Associate February 2016 - December 2017

Yale University Yale Cancer Center (New Haven US)

PhD student 2011- - 2015-

Institute of Cardiovascular and Metabolic Diseases (Toulouse FR)

Education

PhD in biology, health and Biotechnology, with specialization in Pathophysiology 2011- - 2015-

University of Toulouse (Toulouse FR)

Master of Science, Cellular Biology & Physiopathology 2009- - 2011-

University of Bordeaux (Bordeaux FR)

Bachelor of Sciences 2006- - 2009-

University of Bordeaux (Bordeaux FR)

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