Kevin Karplus' research group develops tools and techniques for genome assembly from next-generation sequence data, signal processing and machine learning for nanopores.
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Published articles Show More
Classifying G-protein coupled receptors with support vector machines.
Published in Bioinformatics
Motivation: The enormous amount of protein sequence data uncovered by genome research has increased the demand for computer software that can automate the recognition of new proteins. We discuss the relative merits of various automated methods for recognizing G-Protein Coupled Receptors (GPCRs), a superfamily of cell membrane proteins. GPCRs are fo...
Classifying G-protein coupled receptors with support vector machines.
Published in Bioinformatics
Motivation: The enormous amount of protein sequence data uncovered by genome research has increased the demand for computer software that can automate the recognition of new proteins. We discuss the relative merits of various automated methods for recognizing G-Protein Coupled Receptors (GPCRs), a superfamily of cell membrane proteins. GPCRs are fo...
PREDICT-2ND: a tool for generalized protein local structure prediction.
Published in Bioinformatics