Jorge is currently a graduate student in UCLA's Cellular and Molecular Pathology department while making time for his great wife Teri and beautiful daughter Valeria. Recently, he graduated from California State University Dominguez Hills (CSUDH) with a B.S. in biology. While at CSUDH he worked in Dr. Helen Chun's lab attempting to find the mechanism by which Ataxia Telangectasia Mutated is inactivated. He is a past MBRS-RISE, and MARC-USTAR scholar which allowed me the opportunity to attend national minority research conferences such as ABRCMS and SACNAS. Currently Jorge is researching how microRNAs functionally interact with oncogenes and tumor suppressors to play roles in cancer.
Jorge Contreras
Institution:
Rao Lab
Los Angeles, CA, United States
https://www.mysciencework.com/profile/jorge.contreras
Summary
Published articles Show More
MicroRNA-146a modulates B-cell oncogenesis by targeting Egr1
Published in Oncotarget
miR-146a is a NF-κB induced microRNA that serves as a feedback regulator of this critical pathway. In mice, deficiency of miR-146a results in hematolymphoid cancer at advanced ages as a consequence of constitutive NF-κB activity. In this study, we queried whether the deficiency of miR-146a contributes to B-cell oncogenesis. Combining miR-146a defic...
BALR-6 regulates cell growth and cell survival in B-lymphoblastic leukemia
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Published in Molecular Cancer
Background A new class of non-coding RNAs, known as long non-coding RNAs (lncRNAs), has been recently described. These lncRNAs are implicated to play pivotal roles in various molecular processes, including development and oncogenesis. Gene expression profiling of human B-ALL samples showed differential lncRNA expression in samples with particular ...
MicroRNAs in inflammation and immune responses
Published in Leukemia
MicroRNAs (miRNAs) are important regulators of gene expression in the immune system. In a few short years, their mechanism of action has been described in various cell lineages within the immune system, targets have been defined and their unique contributions to immune cell function have been examined. Certain miRNAs serve in important negative fee...
