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Slowing DNA Transport Using Graphene-DNA Interactions
Published in Advanced Functional Materials
Slowing down DNA translocation speed in a nanopore is essential to ensuring reliable resolution of individual bases. Thin membrane materials enhance spatial resolution but simultaneously reduce the temporal resolution as the molecules translocate far too quickly. In this study, the effect of exposed graphene layers on the transport dynamics of both...
Nanopore-Based Assay for Detection of Methylation in Double-Stranded DNA Fragments
...Published in ACS Nano
DNA methylation is an epigenetic modification of DNA in which methyl groups are added at the 5-carbon position of cytosine. Aberrant DNA methylation, which has been associated with carcinogenesis, can be assessed in various biological fluids and potentially can be used as markers for detection of cancer. Analytically sensitive and specific assays f...
Research Highlights from the last year in nanomedicine
Published in Artificial Cells Nanomedicine and Biotechnology
