Jean Zwiller

Cocaine Regulates the Salt-Inducible Kinase (SIK1) by Inducing Protein Phosphatase-2A Expression in Rat Brain

Published in Journal of Drug and Alcohol Research

We have recently documented that cocaine-induced MEF2C expression in rat brain is mediated by the activation of the salt-inducible kinase SIK1, which is itself regulated by phosphorylation mechanisms. We report here that acute or chronic treatment of rats with cocaine increased the expression of the catalytic subunit of protein phosphatase PP2A in ...