Jaime obtained his Ph.D. from the Albert Einstein College of Medicine with a focus on the biomedical sciences. At Einstein his researched focused in the field of autophagy, specifically centered around one of the three main forms of autophagy, Chaperone-mediated Autophagy (CMA). His research efforts established the first signaliing mechanism discovered to regulate CMA via the retinoic acid-signaling pathway.
In the Rao Lab, Jaime's efforts will focus on studying the overall role of miRNA in B-lymphocyte activation. Specifically, Jaime plans to (1) identify and characterize microRNA-dependent regulation of B-cell activation and terminal differentiation. ; (2) characterize B-lymphomagenesis as a function of tumor suppressor microRNA's; and (3) characterize the molecular mechanisms of miRNA-mediated regulation in B-cell development and B-cell lymphoma.
Jaime Anguiano
Institution:
Rao Lab
Los Angeles, CA, United States
https://www.mysciencework.com/profile/jaime.anguiano
Summary
Published articles Show More
BALR-6 regulates cell growth and cell survival in B-lymphoblastic leukemia
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Published in Molecular Cancer
Background A new class of non-coding RNAs, known as long non-coding RNAs (lncRNAs), has been recently described. These lncRNAs are implicated to play pivotal roles in various molecular processes, including development and oncogenesis. Gene expression profiling of human B-ALL samples showed differential lncRNA expression in samples with particular ...
