Ivan Babic

Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction.

Published in Oncotarget

Metabolic reprogramming is a key feature of tumorigenesis that is controlled by oncogenes. Enhanced utilization of glucose and glutamine are the best-established hallmarks of tumor metabolism. The oncogene c-Myc is one of the major players responsible for this metabolic alteration. However, the molecular mechanisms involved in Myc-induced metabolic...

Multiple spatially related pharmacophores define small molecule inhibitors of OLIG2 in glioblastoma.

Published in Oncotarget