Isabelle Andre-Schmutz
Directeur du laboratoire, Human Lymphohematopoiesis Lab
Institution:
USPC - SET - SVS
Summary
Published articles Show More
Gene Therapy with Hematopoietic Stem Cells: The Diseased Bone Marrow's Point of View
Published in Stem Cells and Development
When considering inherited diseases that can be treated by gene transfer into hematopoietic stem cells (HSCs), there are only two in which the HSC and progenitor cell distribution inside the bone marrow and its microenvironment are exactly the same as in a healthy subject: metachromatic leukodystrophy (MLD) and adrenoleukodystrophy (ALD). In all ot...
B cells differentiate in human thymus and express AIRE
...Published in Journal of Allergy and Clinical Immunology
Letter to the editor
Alterations of circulating lymphoid committed progenitor cellular metabolism after allogeneic stem cell transplantation ...
Published in Experimental Hematology
Lymphoid-committed CD34(+)lin(-)CD10(+)CD24(-) progenitors undergo a rebound at month 3 after allogeneic hematopoietic stem cell transplantation (allo-HSCT) in the absence of acute graft-versus-host disease (aGVHD). Here, we analyzed transcriptional programs of cell-sorted circulating lymphoid-committed progenitors and CD34(+)Lin(-)CD10(-) nonlymph...
Theses Show More
Génération des progéniteurs lymphoïdes T ex vivo par exposition brève au ligand de Notch DL-4
L’allogreffe des cellules souches hématopoïétiques (CSH) dans les situations d’incompatibilité HLA partielle représente une option thérapeutique irremplaçable pour des patients nécessitant une greffe de cellules souches hématopoïétiques, en absence d’un donneur HLA-identique. Toutefois, le retard de la restauration du système immunitaire en particu...
Experience
Directeur du laboratoire
université Paris Descartes
Human Lymphohematopoiesis Lab; UMR_S 1163, IHU IMAGINE, Institut des maladies génétiques
