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Iosif Pediaditakis

Summary

Dr. Pediaditakis is the Associate Director of Neuroscience at Alchemab Therapeutics, a biotech company developing novel products for patients with hard-to-treat diseases by harnessing the power of naturally protective antibodies. Prior to joining Alchemab, he was the Associate Director of Complex Physiological Systems at Vesalius Therapeutics, where he led the development, design, and implementation of new human cell-based complex in vitro models in the preclinical stage of drug development. Before joining Vesalius, Dr. Pediaditakis was Associate Director of Research at Emulate Inc., a Harvard spinoff. He led the neuroscience team to develop next-generation tissue chip models of neuroinflammation and Parkinson's disease. He utilized induced pluripotent stem cells to incorporate blood vessel cells, neurons, astrocytes, and microglia into perfuseable micro-engineered 3D environments to model human brain function, blood-brain barrier physiology and uncover novel biomarkers of neurodegenerative diseases. Prior to Emulate, Dr. Pediaditakis completed his postdoctoral fellowship at the Medical School of the University of Crete and the Institute of the Foundation for Research and Technology-Hellas, where he spearheaded the development of a new family of synthetic, BBB-permeable neurotrophic receptor agonists as a potential treatment for a wide range of neurological disorders, including ALS, Alzheimer's, and Parkinson's disease. Dr. Pediaditakis has broad expertise in neuropharmacology and Organs-on-Chips technology.

-The human Brain-Chip Dr. Pediaditakis developed at Emulate Inc was recognized as one of The Scientist's Top 10 Innovations of 2021.

-Dr. Pediaditakis has been named as one of Greek America's Forty Under 40 for the Class of 2022.

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Experience

Associate Director, Neuroscience Since December 2022

Neuroscience 

Associate Director, Neuroscience Since December 2022

Dr. Pediaditakis is the Associate Director of Neuroscience at Alchemab Therapeutics, a biotech company developing novel products for patients with hard-to-treat diseases by harnessing the power of naturally protective antibodies. 

Associate Director 2021 - 2022

Flagship Pioneering (Cambridge US)

• Led the development, design, and implementation of new human cell-based complex in vitro models in the preclinical stage of drug development.

• Provide Stem Cell biology expertise to project teams and assist in optimizing stem cell differentiation into neuronal and glial cells.

• Established and managed collaborations with CROs to expand the in-house stem cell capacities (induced pluripotent stem cell reprogramming).

• Member of a cross-functional target team responsible for evaluating and nominating new targets.

Associate Director of Research 2019- - 2021-

Emulate Inc (Cambridge US)

Principal Scientist 2018- - 2019-

Emulate Inc. (Boston US)

Education

Awards

Greek America’s Forty Under 40 2022

The awards recognize those who have excelled in their professional endeavors while simultaneously showing care and concern for the world around them through philanthropic initiatives.

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