François Boussin
Responsable du laboratoire, Laboratoire de RadioPathologie
Institution:
USPC - SET - SVS
Summary
Published articles Show More
Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression.
...Published in Journal of Hepatology
The ADP ribosyl transferase [poly(ADP-ribose) polymerase] ARTD3(PARP3) is a newly characterized member of the ARTD(PARP) family that catalyzes the reaction of ADP ribosylation, a key posttranslational modification of proteins involved in different signaling pathways from DNA damage to energy metabolism and organismal memory. This enzyme shares high...
Bone marrow-derived stem cells do not reconstitute spermatogenesis in vivo.
Published in STEM CELLS
Targeting human telomerase for cancer therapeutics.
...Published in Liver international : official journal of the International Association for the Study of the Liver
The enzyme telomerase is involved in the replication of telomeres, specialized structures that cap and protect the ends of chromosomes. Its activity is required for maintenance of telomeres and for unlimited lifespan, a hallmark of cancer cells. Telomerase is overexpressed in the vast majority of human cancer cells and therefore represents an attra...
Theses Show More
Experience
Responsable du laboratoire
Université Paris Diderot
Laboratoire de RadioPathologie; Service Cellules Souches et Radiation (SCSR); UMR 967 (CEA Fontenay), Institut de Radioprotection Cellulaire et Moléculaire; UFR Sciences du Vivant
