Fernando Rodrigues-Lima

Activation of the aryl hydrocarbon receptor by carcinogenic aromatic amines and modulatory effects of their N-acetylated...

Published in International Archives of Orthopedic Surgery

Effects of pesticide chemicals on the activity of metabolic enzymes: focus on thiocarbamates.

Published in New in Ophthalmology № 2 2017

Many advances in the study of thiocarbamates metabolism and reactivity have led to a better knowledge of biological effects of these compounds. However, more data are needed on the determination of targets and specificity. Only few data concerning the exposure to a cocktail of pesticides/chemicals are available, raising the need to evaluate the tox...

Structural and functional characterization of an arylamine N-acetyltransferase from the pathogen Mycobacterium abscessus...

Published in The American Journal of Human Genetics

Mycobacterium abscessus is the most pathogenic rapid-growing mycobacterium and is one of the most resistant organisms to chemotherapeutic agents. However, structural and functional studies of M. abscessus proteins that could modify/inactivate antibiotics remain nonexistent. Here, the structural and functional characterization of an arylamine N-acet...