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Diabetic cornea wounds produce significantly weaker electric signals that may contribute to impaired healing.
Published in Scientific Reports
Wounds naturally produce electric signals which serve as powerful cues that stimulate and guide cell migration during wound healing. In diabetic patients, impaired wound healing is one of the most challenging complications in diabetes management. A fundamental gap in knowledge is whether diabetic wounds have abnormal electric signaling. Here we use...
Measurement of extracellular ion fluxes using the ion-selective self-referencing microelectrode technique.
Published in Journal of Visualized Experiments
Cells from animals, plants and single cells are enclosed by a barrier called the cell membrane that separates the cytoplasm from the outside. Cell layers such as epithelia also form a barrier that separates the inside from the outside or different compartments of multicellular organisms. A key feature of these barriers is the differential distribut...