Impact of the HIV integrase genetic context on the phenotypic expression and in vivo emergence of raltegravir resistance...
Published in Diseases of the Colon & Rectum
The emergence of different resistance mutations in patients was in full agreement with the impact of mutations in different baseline integrase contexts. Evolution towards different resistance genotypes is thus largely determined by the capacity of different integrase sequences present at baseline to minimize the effect of mutations on virus RC whil...
Impact of the HIV integrase genetic context on the phenotypic expression and in vivo dynamics of integrase inhibitor res...
Responsable de l'équipe
Virus evolution and pathogenesis; UMR941, Génétique des virus et pathogenèse des maladies virales; Institut Universitaire d'Hématologie (IUH)
Faculty of Biology