After a master degree in Medical Biotechnology from the University of Padua (Italy), I obtained a PhD in Biomedical Science-Neurobiology from the Universities of Padua and Bordeaux (France). During this time I focused on new biomolecular probes to screen therapeutic agents against Alzheimer's Disease. My PhD allowed me also to study the regulation of cellular calcium levels by Presenilins, and by the natural compound curcumin. After some experience as a Science Teacher, I started working as a Post-Doctoral fellow in the University of Udine (Italy) where my work focused on new therapeutic strategies against glioblastoma and on the regulation of the protein HDAC4. I currently work in Luxembourg as a member of the Cancer Epigenetic team at the Laboratoire de Biologie Molécularie et Cellulaire du Cancer (LBMCC). My current research aims at finding new epigenetic modulators for cancer treatment. ...
Cristina Florean
Member of the Cancer Epigenetic team, Medical Biotechnology
Institution:
LBMCC
LBMCC, Luxembourg, Luxembourg
https://www.mysciencework.com/profile/cristina.florean
Summary
Published articles Show More
Epigenomics of leukemia: from mechanisms to therapeutic applications
Published in Epigenomics
Leukemogenesis is a multistep process in which successive transformational events enhance the ability of a clonal population arising from hematopoietic progenitor cells to proliferate, differentiate and survive. Clinically and pathologically, leukemia is subdivided into four main categories: chronic lymphocytic leukemia, chronic myeloid leukemia, a...
Redox regulation – Natural compound as regulators of inflammation signaling
Published in Biochemical Pharmacology
Class IIa HDACs: from important roles in differentiation to possible implications in tumourigenesis
Published in Journal of Cellular and Molecular Medicine
Experience
Education
PhD in Biomedical Science January 2006 - February 2009
UUniversità degli study di Padova (Padova IT)
Joint degree delivered by Italy and France (Bordeaux). Co-tutored Vinci program.
Master degree in Medical Biotechnology January 1999 - March 2005
Università degli Studi di Padova (Padova IT)
5 years degree studies, 1 year of practical training.