Our adaptive immune systems is highly efficient in protecting us from the most diverse intruders. B cells are an essential part of the adaptive immune system. Each B cell uniquely rearranges its genome several times to produce an unique antibody. Until very recently, the analysis of B cell populations circulating in the periphery at any given time was labor intensive and low throughput. The Vollmers lab focuses on developing DNA sequencing tools to analyze B cells on a population and single cell level.