CNRS UMR 7622
Published in Epigenetics & Chromatin
Background: Cyclins and cyclin-dependent kinases (CDKs) are essential for cell cycle regulation and are functionally associated with proteins involved in epigenetic maintenance of transcriptional patterns in various developmental or cellular contexts. Epigenetic maintenance of transcription patterns, notably of Hox genes, requires the conserved Pol...
A sequence variation in the promoter of the placental alkaline phosphatase gene (ALPP) is associated with allele-specifi...
Published in Placenta
Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta. This enzyme displays strong genetic variability. Some of the variants were reported to be associated with pathology of pregnancy. We show here that the two most common ALPP allelic variants, Pl 1 and Pl 2 , differ in mRNA expression level...
Post-doctoral Research Fellow Since August 2015
University of Birmingham (Birmingham GB)
Dr Yun Fan - Regulation of apoptosis and compensatory cell proliferation in tissue homeostasis
PhD Candidate in Genetics October 2011 - September 2015
Cyclin G and maintenance of tissue homeostasis during development in Drosophila melanogaster.
Internship February 2011 - July 2011
Investigated the role of Drosophila melanogaster Cyclin G in the interplay between cell cycle and epigenetic regulation of gene expression.
Internship October 2010 - January 2011
Laboratoire de Génétique et de Biologie Cellulaire (Paris area FR)
Studied the role of GAGA, Batman and Pipsqueak in the recrutment of epigenetic factors and maintenance of gene expression in Drosophila melanogaster.
Internship January 2010 - April 2010
Unité de Pathologie Cellulaire et Génétique (Paris area FR)
Analyzed a polymorphism in the promoter of the placental alkaline phosphatase gene in human term placenta.
PhD in Genetics Since October 2011
UPMC - Sorbonne Universities (Paris FR)
Project: Cyclin G and maintenance of tissue homeostasis during development in Drosophila melanogaster.
Master's degree September 2006 - July 2011
Université de Versailles Saint Quentin en Yvelines (Paris area FR)
Genetics, Molecular Biology, Cell Biology
Fondation ARC October 2015
1 year PhD fellowsip