Human T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activi...
Keywords: human T-cell leukemia virus type-1, adult T-cell leukemia, HBZ, histone acetyl transferase activity, p53 ABSTRACT Adult T-cell leukemia (ATL) is an often fatal malignancy caused by infection with the complex retrovirus, human T-cell Leukemia Virus, type 1 (HTLV-1). In ATL patient samples, the tumor suppressor, p53, is infrequently mutated...
Selectivity of ORC binding sites and the relation to replication timing, fragile sites, and deletions in cancers
Published in Clinical Lymphoma Myeloma & Leukemia
Published in Acta Biochimica et Biophysica Sinica
Responsable de l'équipe Since 2015
Epigénétique, Réplication de l'ADN et Cancer; Développement, Reproduction, Cancer (DRC); UMR 8104 / UMR_S1016, Institut Cochin; Faculté de Médecine