Bioinformatics, Biostatistics
Anthoula Gaigneaux
bioinformatician
Summary
Published articles Show More
Early downregulation of Mcl-1 regulates apoptosis triggered by cardiac glycoside UNBS1450
Published in Cell Death and Disease in Jun 07, 2015
Cardiac glycosides (CGs), prescribed to treat cardiovascular alterations, display potent anti-cancer activities. Despite their well-established target, the sodium/potassium (Na + /K +)-ATPase, downstream mechanisms remain poorly elucidated. UNBS1450 is a hemi-synthetic cardenolide derived from 2″-oxovorusharin extracted from the plant Calotropis ...
The infrared spectrum of human glioma cells is related to their in vitro and in vivo behavior
Published in Experimental Cell Research
The present research investigates whether infrared spectra can be related to the biological characteristics of glioma cell lines. We used nine human glioma cell lines for which a series of in vitro and in vivo biological features had already been established [Glia 36 (2001) 375] and were able to show that their characteristic infrared spectra refle...
Cell Discrimination by Attenuated Total Reflection–Fourier Transform Infrared Spectroscopy: The Impact of Preprocessin...
Published in Applied Spectroscopy
Fourier transform infrared (FT-IR) spectroscopy has become a powerful tool for biodiagnostics and cell line classification. Typical experimental perturbations included in spectra are baseline shift and scale variation between spectra. They have to be removed by data preprocessings to allow further data analysis and classification. In this work, we ...
Experience
bioinformatician Since October 2010
Laboratoire de Biologie Moléculaire et Cellulaire du Cancer (LBMCC) (Luxembourg LU)
bioinformatician