Angela Brooks Jl, Aspden Ai, Podgornaia Dc, Rio Se, Brenner
Published in
RNA
RNA sequence elements involved in the regulation of pre-mRNA splicing have previously been identified in vertebrate genomes by computational methods. Here, we apply such approaches to predict splicing regulatory elements in Drosophila melanogaster and compare them with elements previously found in the human, mouse, and pufferfish genomes. We identi...
Consortium, Modencode S, Roy J, Ernst Pv, Kharchenko P, Kheradpour N, Negre Ml, Eaton Jm, Landolin Ca, Bristow L, Ma
...
Published in
Science
To gain insight into how genomic information is translated into cellular and developmental programs, the Drosophila model organism Encyclopedia of DNA Elements (modENCODE) project is comprehensively mapping transcripts, histone modifications, chromosomal proteins, transcription factors, replication proteins and intermediates, and nucleosome propert...
Br, Graveley Angela Brooks Jw, Carlson Mo, Duff Jm, Landolin L, Yang Cg, Artieri Mj, Van Baren N, Boley Bw, Booth
...
Published in
Nature
Drosophila melanogaster is one of the most well studied genetic model organisms; nonetheless, its genome still contains unannotated coding and non-coding genes, transcripts, exons and RNA editing sites. Full discovery and annotation are pre-requisites for understanding how the regulation of transcription, splicing and RNA editing directs the develo...
