THERAPEUTIC AND PROPHYLACTIC AGENT FOR GLIOMA, BRAIN TUMOR MALIGNANCY MARKER, BRAIN TUMOR PROGNOSTIC MARKER, METHOD FOR DETERMINING MALIGNANCY AND PROGNOSIS OF BRAIN TUMOR AND ANTIBODY INHIBITING TUMOR PROLIFERATION
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Applicant
The University of Tokyo
Applicant
Yamaguchi University
Representative
Application number
EP19906351A1
Kind
A1
Document number
3936149
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THERAPEUTIC AND PROPHYLACTIC AGENT FOR GLIOMA, BRAIN TUMOR MALIGNANCY MARKER, BRAIN TUMOR PROGNOSTIC MARKER, METHOD FOR DETERMINING MALIGNANCY AND PROGNOSIS OF BRAIN TUMOR AND ANTIBODY INHIBITING TUMOR PROLIFERATION

3936149 - EP19906351A1 - EPO

Application Dec 27, 2019 - Publication Jan 12, 2022

Kohei MIYAZONO Ryo TANABE Masato MORIKAWA Carl-Henrik HELDIN Bengt WESTERMARK Koji TAMADA

Abstract

An object of the present invention is to provide a novel agent for treating or preventing a glioma, to provide a marker for malignancy of a brain tumor and a prognostic marker for a brain tumor, and to provide a method for determining malignancy of a brain tumor and a method for determining a prognosis for a brain tumor patient. According to the present invention, there are provided an agent for treating or preventing a glioma comprising an HVEM inhibitor as an active ingredient; a marker for malignancy of a brain tumor and a prognostic marker for a brain tumor, each comprising an HVEM protein or an HVEM gene; and a method for determining malignancy of a brain tumor and a method for determining a prognosis for a brain tumor patient, each comprising measuring an HVEM expression amount in a biological sample of a subject.

Description

Claims

Patent References

Patent Publication Date Title
JP2018248465A N/A N/A
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