METHOD FOR PREPARING LIVE ATTENUATED VACCINE BY RADIATION AND LIVE ATTENUATED VACCINE COMPOSITION PREPARED THEREBY
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Applicant
Korea Atomic Energy Research Institute
Representative
Maiwald Patent- und Rechtsanwaltsgesellschaft mbH
Application number
EP19886054A1
Kind
A1
Document number
3909610
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METHOD FOR PREPARING LIVE ATTENUATED VACCINE BY RADIATION AND LIVE ATTENUATED VACCINE COMPOSITION PREPARED THEREBY

3909610 - EP19886054A1 - EPO

Application Jan 08, 2019 - Publication Nov 17, 2021

Ho-Seong SEO Sang-Yong LIM Jong-Hyun JUNG

Abstract

The present invention relates to a method of preparing a live attenuated vaccine by irradiation and a live attenuated vaccine composition prepared by the same, and more particularly, a method of preparing a live attenuated vaccine by irradiation including irradiating a pathogenic microorganism with a dose of 0.5 to 2kGy of radiation per single radiation six to fifteen times; and a live attenuated vaccine composition including a pathogenic microorganism attenuated to not be revertant to a wild type by generation of at least one mutation of nucleotide insertion and nucleotide deletion by irradiation.

Description

Claims

Patent References

Patent Publication Date Title
14665107 29/08/2017 Compositions Containing Ambient-Temperature Stable, Inactivated but Therapeutically Active Biopharmaceuticals and Methods for Formulation Thereof
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