CHIMERIC ANTIGEN RECEPTORS TARGETING CD-19
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Grantee
Department of Health and Human Services The U.S.A. as represented by the Secretary
Representative
Martin Huenges
Application number
EP15729304B1
Kind
B1
Document number
3149044
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CHIMERIC ANTIGEN RECEPTORS TARGETING CD-19

3149044 - EP15729304B1 - EPO

Application Jun 01, 2015 - Publication Oct 21, 2020

James N. KOCHENDERFER

Description

Claims

Patent References

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Other References

  • NICHOLSON I C ET AL: "Construction and characterisation of a functional CD19 specific single chain Fv fragment for immunotherapy of B lineage leukaemia and lymphoma", MOLECULAR IMMUNOLOGY, PERGAMON, GB, vol. 34, no. 16-17, 1 November 1997 (1997-11-01), pages 1157-1165, XP002220979, ISSN: 0161-5890, DOI: 10.1016/S0161-5890(97)00144-2 cited in the application
  • BRENTJENS R J ET AL: "Novel cellular therapies for leukemia: CAR-modified T cells targeted to the CD19 antigen", HEMATOLOGY, AMERICAN SOCIETY OF HEMATOLOGY, WASHINGTON, DC, US, vol. 2012, 1 January 2012 (2012-01-01), pages 143-151, XP002727327, ISSN: 1520-4391, DOI: 10.1182/ASHEDUCATION-2012.1.143
  • R. J. BRENTJENS ET AL: "Genetically Targeted T Cells Eradicate Systemic Acute Lymphoblastic Leukemia Xenografts", CLINICAL CANCER RESEARCH, vol. 13, no. 18, 12 September 2007 (2007-09-12), pages 5426-5435, XP055204921, ISSN: 1078-0432, DOI: 10.1158/1078-0432.CCR-07-0674
  • LITTMAN D R ET AL: "The isolation and sequence of the gene encoding T8: A molecule defining functional classes of T lymphocytes", CELL, ELSEVIER, AMSTERDAM, NL, vol. 40, no. 2, 1 February 1985 (1985-02-01), pages 237-246, XP023910638, ISSN: 0092-8674, DOI: 10.1016/0092-8674(85)90138-2 [retrieved on 1985-02-01]
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