BI-SPECIFIC ANTIBODIES AND USES THEREOF
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Applicant
Academia Sinica
Applicant
Kaohsiung Medical University
Representative
Ter Meer Steinmeister & Partner
Application number
EP20169429A1
Kind
A1
Document number
3725812
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BI-SPECIFIC ANTIBODIES AND USES THEREOF

3725812 - EP20169429A1 - EPO

Application Mar 02, 2015 - Publication Oct 21, 2020

Steven R. Roffler Tian-Lu Cheng Chien-Han Kao Bing-Mae Chen Yu-Cheng Su Hsin-Yi Tung Kuo-Hsiang Chuang

Abstract

Disclosed herein is a bi-specific antibody that specifically directs a therapeutic agent to a cancer cell by targeting a tumor antigen of the cancer cell, and thereby suppresses the growth of the cancer or blocking the invasion or metastasis of the cancer. The bi-specific antibody of the present disclosure includes a first antigen binding site that binds to polyethylene glycol (PEG); and a second antigen binding site that binds to a target ligand, such as a tumor antigen.

Description

Claims

Patent References

Patent Publication Date Title
12253895 28/06/2011 Cd19 Binding Agents and Uses Thereof
EP10176938A1 15/06/2011 Human anti-epidermal growth factor receptor antibody
EP10009151A1 08/12/2010 High affinity human antibodies to c-erbB-2
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