Sorbonne Universités, UPMC Univ. Paris 6, CNRS, Laboratoire Interfaces et Systèmes Electrochimiques, 75005, Paris, France

Radio-frequency plasma polymerized biodegradable carrier for in vivo release of cis-platinum

Published in Oncotarget

A low pressure plasma process based on plasma deposition has been used todevelop a drug delivery strategy. In this study, a drug delivery system based ondifferent layers of plasma co-polymerized Poly ε-caprolactone-Polyethylene glycol(PCL-PEG) co-polymers was deposited on biocompatible substrates. Cis-platinum(118 μgm/cm2) was used as an anti-cance...