Sorbonne Paris Cité Universités, UMR Univ. Paris 7, INSERM U965 Carcinose, Angiogenèse et Recherche Translationnelle, L'Hôpital Lariboisière, 75010, Paris, France

Radio-frequency plasma polymerized biodegradable carrier for in vivo release of cis-platinum

Published in Oncotarget

A low pressure plasma process based on plasma deposition has been used todevelop a drug delivery strategy. In this study, a drug delivery system based ondifferent layers of plasma co-polymerized Poly ε-caprolactone-Polyethylene glycol(PCL-PEG) co-polymers was deposited on biocompatible substrates. Cis-platinum(118 μgm/cm2) was used as an anti-cance...