Department of Chemistry , University of Utah , 315 South 1400 East , Salt Lake City , UT 84112 , USA

Using IR vibrations to quantitatively describe and predict site-selectivity in multivariate Rh-catalyzed C–H functionali...

Published in Chemical Science

Achieving selective C–H functionalization is a significant challenge that requires discrimination between many similar C–H bonds. Yet, reaction systems employing Rh2(DOSP)4 and Rh2(BPCP)4 were recently demonstrated to afford high levels of selectivity in the C–H insertion of carbenes into toluene-derived substrates. Herein, we explore the origin of...