Department of Chemistry, University of Iowa , Iowa City, Iowa 52242, United States.

Structural and Kinetic Studies of Formate Dehydrogenase from Candida boidinii.

Published in Biochemistry

The structure of formate dehydrogenase from Candida boidinii (CbFDH) is of both academic and practical interests. First, this enzyme represents a unique model system for studies on the role of protein dynamics in catalysis, but so far these studies have been limited by the availability of structural information. Second, CbFDH and its mutants can be...